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So far, bariatric surgery has proven to be the most effective approach to body weight (BW) reduction, as a recent network meta-analysis demonstrated that it was associated with a 17.7% greater BW loss compared to lifestyle intervention/medical therapy 6 , with substantial improvements or remission of T2D, dyslipidemia and hypertension 7
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Despite the fact that the relationship between glucagon and body weight is well established, some research found no changes in food intake following glucagon administration, which suggests that appetite-independent mechanisms may play a role in the glucagon-mediated regulation of body weight [14]
(PubMed) Costell M, O'Connor JE, Grisolia S
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