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Systemic allergic signs that require emergency medical attention include widespread hives across multiple body areas, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, rapid heartbeat or feeling faint, and dizziness or confusion
However, we mitigated the potential confounding effect of CAD through the use of MR analysis and by rigorously selecting genetic instruments that were strongly associated with GLP-1RAs, while excluding SNPs associated with CAD and other pleiotropic pathways
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