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A: For best results, apply at night before bed

The contributions of LC and TMAO to adverse cardiac events, such as MI, stroke, sudden cardiac death (SCD), and HF, have come under more and more scrutiny in research as seen in Table 3

Patients should be counseled to: Consume smaller, more frequent meals (56 per day) rather than large portions Emphasize low-fat, low-fiber foods that empty more readily from the stomach Ensure adequate hydration, particularly with liquid calories if solid food tolerance is poor Avoid lying down immediately after meals Chew food thoroughly and eat slowly For patients developing concerning symptoms, temporary dose reduction or treatment interruption may be necessary

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