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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)
PMID 27468410
Its important to talk to doctors about B12 treatment plans
meaning that animal studies have shown some adverse effect or there are no well-controlled studies in humans, but potential benefits may warrant use despite potential risks
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