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Traditionally, mechanistic research on SCFA-mediated GLP-1 secretion, particularly for butyrate, has centered on cell membrane receptor pathways (e.g., GPR41/43/109a) or epigenetic regulation (HDAC inhibition) (Tolhurst et al., 2012
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FOX04 The curiously named Forkhead box O4, FOX04 , is a protein that is involved in regulating various cellular processes, including cell cycle arrest, apoptosis, DNA repair, stress response, metabolism, and longevity (Huang, 2021)
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