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Lancet, 376 (9750), 14171427
Cytochrome P450 monooxygenases (P450) and carboxylesterases (CarEs) belong to phase I metabolizing enzymes that catalyze xenobiotics and endobiotics mainly through hydroxylation/oxidation reactions ( in situ selectivity in hydroxylation, epoxidation, dealkylation, sulfoxydation, deamination, desulphuration, dehalogenation, and nitro reduction (Xu et al., 2005)
Toni N, Teng EM, Bushong EA, Aimone JB, Zhao C, Consiglio A, et al
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