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doi: 10.1016/j.bbalip.2013.06.007 Summary Keywords L-carnitine, dairy cow, mid-lactation, lipopolysaccharide, PBMC Citation Seemann L, Kersten S, Bhler S, Billenkamp F, Meyer U, Visscher C, Huber K, Most E, Eder K, Dnicke S and Frahm J (2025) Dietary supplementation with L-carnitine elevates intracellular carnitine levels and affects gene expression of SLC25A20 and COX4I1, as well as non-mitochondrial respiration of bovine blood cells during systemic immune challenge

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2.1.3 Inhibited pyroptosis and inflammation of follicular granulosa cells Furthermore, researchers have discovered that metformin has the potential to enhance follicle development and induce ovulation by suppressing pyroptosis and inflammation of follicular granulosa cells