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The current results show that number needed to benefit (NNTB) was 207 (95%CI: NNTB 129 to NNTB 620, Follow-up time: 3.48 1.51 years) for total MI, NNTB 67 (95%CI: NNTB 46 to NNTB 135, Follow-up time: 3.48 1.51 years) for MACE, NNTB 170 (95%CI: NNTB 120 to NNTB 306, Follow-up time: 3.48 1.51 years) for cardiovascular mortality, and NNTB 93 (95%CI: NNTB 52 to NNTB 1717, Follow-up time: 3.45 1.21 years) for coronary revascularization

While there is no universally set BMI for prescribing Ozempic for weight loss, it is generally reserved for those classified as overweight or obese, especially in the presence of other health issues

Different doses and escalation schedules of retatrutide were evaluated in 2 phase 2 American trials of subjects with obesity (n=338) and type 2 diabetes (n=281)