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In line with reports indicating that PPAR may act on hypothalamic neurocircuitries 5,6 , we identified a series of new PPAR protein targets in the hypothalamus that are acutely upregulated by tesaglitazar and by GLP-1RA/tesaglitazar, but not by treatment with the GLP-1RA
It plays a pivotal role in energy production by transporting fatty acids into the mitochondria, where they can be burned for energy
JPEN J Parenter.Enteral Nutr 1988;12(6):555-562
Positive coverage in the media has also reduced the stigma around the drugs, which makes them feel safer and more the norm, than something which is new, frightening and potentially problematic
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