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Cabergoline, a D2R-selective agonist, produces a dose-dependent suppression of food intake in wild-type mice and in ghrelin KO mice, but has no effect on food intake in GHSR KO mice (Kern et al., 2012)
LIRA + GIPR-antag induced additional weight loss and food intake suppression compared with LIRA alone
Heres a more detailed look at the administration process: 1
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