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The 2024 ADA Standards of Care note that metformin remains preferred as initial monotherapy when cost, access, and tolerability are considered 5

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If accuracy at low doses is a concern, some prescribers deliberately start patients on the 8mg/mL vial for the first four to eight weeks, then switch to 17mg/mL for higher doses

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For long-term preservation, freezing at -20C is recommended

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Uric Acid Induces a Proatherothrombotic Phenotype in Human Endothelial Cells by Imbalancing the Tissue Factor/Tissue Factor Pathway Inhibitor Pathway

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