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For these reasons, the WHO calls for strategies to increase access to the medications, tiered pricing as well as voluntary licensing

Across SELECT, STEPlike trials, pediatric obesity studies, and ESSENCE, Wegovy demonstrates robust, durable weight loss, clinically meaningful CV risk reduction, and promising liver histologic responses, albeit with an established GIdominant tolerability profile and specific but manageable safety concerns

Patients should be counseled to use only FDA-approved formulations and to verify their prescription matches the pen device they receive

For weight management or more pronounced glucose control, the dose may be gradually increased to 1.0 mg or higher over several weeks