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Canagliflozin did not statistically significantly increase the risk for lower-limb amputations, fractures, acute kidney in- jury, or hyperkalemia but did increase the risk for diabetic ketoacidosis (2.2 and 0.2 events per 1000 patient-years in the canagliflozin and placebo groups, respectively)

This is especially relevant for endpoints such as viability, migration, and tube formation, which can be sensitive to culture conditions and reagent variability

Adherence to mediterranean diet and prevalence of differentiated thyroid cancer: a single-center unit of thyroid surgery experience in a Southern-Italy cohort

Both drugs cause stomach-related side effects, mostly nausea, diarrhea, and vomiting