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doi:10.1016/j.otc.2017.11.006
Additionally, it is now known that pro-inflammatory cytokines also hijack IGF-1 intracellular signalling by phosphorylating serine residues on insulin related substrate (IRS) molecules and hence impeding their binding to IGF-1R [124]
GABA is a neurotransmitter that plays a significant role in the central nervous system and is known to reduce the incidence of cognitive disorders
NO activates soluble guanylate cyclase [174], resulting in the generation of cGMP, which in turn activates cGKI [175]
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