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Diabetes 57:13401348 Shu L, Matveyenko AV, Kerr-Conte J, Cho JH, McIntosh CH, Maedler K (2009) Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function
Furthermore, MSM can increase the monolayer transepithelial electrical resistance and upregulate the expression of tight junction proteins (occludin, claudin-1, and zonula occludens-1), while reducing the permeability of porcine intestinal epithelial cells [43]
Sapients next-generation discovery metabolomics and proteomics can provide an unprecedented view into metabolic and protein changes induced by GLP-1 agonists, offering invaluable insights that can speed development and differentiate the market positioning of a therapy
Kalra S, Baruah MP, Sahay RK, Unnikrishnan AG, Uppal S, Adetunji O
