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These findings suggest a mechanism of FKBP5-mediated chemoresistance that involves intricate proteinprotein interactions and transcriptional regulation, suggesting promising therapeutic opportunities for addressing drug resistance in ovarian cancer

The most common side effects include: Nausea (especially after dose increases) Diarrhea Constipation Vomiting Stomach discomfort or bloating Fatigue In the OASIS 4 trial, serious adverse events actually occurred less frequently with oral semaglutide than with placebo (3.9% vs

J Biol Chem 272 :74457454

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