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Phosphodiesterase-5 inhibitors remain appropriate adjuncts
Patients known to react to TMP-SMX should avoid both trimethoprim and sulfamethoxazole
Product format This product is supplied as a lyophilised research compound
Methods We searched PubMed, Embase, Cochrane and ClinicalTrials.gov up until 27 October 2021 for randomised controlled trials with a duration of at least 12 weeks that compared once-weekly tirzepatide 5, 10 or 15 mg with placebo or other glucose-lowering drugs in adults with type 2 diabetes irrespective of their background glucose-lowering treatment
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