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Intravenous catheters were placed in the forearms of the participants for blood collection at d 0.30, 0.50, 1.0, 2.0, 4.0, 6.0, 8.0, 12.0 hours, and 24.0 hours post-drug cocktail administration

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The skin is exposed every day to factors that increase oxidative stress, including UV rays, pollution, inflammation, environmental stress, and disruption of the skin barrier

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