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In conclusion, intestinal fungal dysregulation, mycobiome-derived metabolites, and the hosts antifungal immune response are key factors in the severity and prognosis of ALD, providing promising targets for future antifungal or immunomodulatory treatments
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Against this backdrop of investor exuberance, 2024 also delivered a dose of realism to temper runaway excitement about many novel AOM assets purported best-in-class profile, often based on nothing more than limited topline data from phase 1 trials
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