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On the other hand, GLP-1 RA can reduce epicardial fat and semaglutide 2.4 mg have shown to improve physical function and symptoms in people with HFpEF [93]
Muri J, Kopf M
Both in vivo and in vitro studies demonstrated that liraglutide treatment inhibited the activation of NLRP3 inflammasome in the lungs of pulmonary fibrosis model mice and in profibrotic cytokine-challenged fibroblasts
hyperglycemia acts directly on glomerular podocytes to increase their permeability to albumin [85, 86], and its correction should reduce urinary protein excretion
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