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Parkin ubiquitinates outer mitochondrial membrane proteins, including voltage-dependent anion channel 1 (VDAC1) and mitofusins (Mfn1 and Mfn2), thereby initiating mitophagy
For in vitro studies, researchers typically reconstitute with bacteriostatic water (0.9% benzyl alcohol) or, for cell-culture protocols, with sterile water at a concentration matched to the assay
If youre curious about supplements for supporting GLP-1, consider them a small complement to wholefood habits, and always discuss with a healthcare professional first
Pharmaceuticals 15 , 626 (2022)
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