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Ensure that your reduced-calorie diet remains nutritionally complete

However, one important consideration is the risk of hypoglycemia, or low blood sugar, when combining glucose-lowering medications

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During phase 1 trials in NASH patients, efocipegtrutide showed a half-life of around 5.9 days, and was capable of reducing body weight by 5.1% when administered weekly at 0.08mg/kg, after 12 weeks [36]