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[] Further investigation into CV and renal benefits is underway, particularly concerning heart failure and chronic kidney disease, with ongoing research assessing whether these benefits extend to nondiabetic populations

proposed that the research on the treatment for immune-mediated diseases, such as rheumatoid arthritis, should attempt to achieve a more comprehensive understanding of various disease-related biomarkers, conducting large-scale high-throughput data analysis, and identifying and quantifying the disease metabolites (37)

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