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Ketoacidosis during a low-carbohydrate diet
The increased understanding of activation pathways and related ECD conformations may inspire the design of new molecules targeting the ECDECL interface
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Despite the limitation of this study due to the restricted metabolic coverage of only hydrophilic molecules, our findings suggest that the molecule metabolic differences in PsA sera compared to healthy conditions contribute to elucidating the role of metabolite unbalance on the inflammatory burden, oxidative stress, energy and collagen metabolism but also on peculiar features of PsA disease, as metabolic disorder and diabetes
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