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[9] Its also prudent to be cautious or avoid NAD+ injections if you have a serious uncontrolled medical condition (for example, end-stage liver or kidney disease or severe heart disease), unless your physician specifically determines its safe

Any individual considering these compounds for this purpose should do so under the supervision of a qualified clinician with imaging confirmation of tear grade and location, realistic expectations calibrated to the mechanistic evidence rather than anecdotal outcomes, and a concurrent physiotherapy program to ensure that any repaired tissue is appropriately loaded for maturation