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doi: 10.1016/j.ando.2022.12.423
The B Vitamins are co-factors in the production of red blood cells, DNA synthesis as well as the production of the myelin sheath that surrounds the nerves
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E., Maier, A
Both intrinsic factors, properties arising in the malignant cells, such as MYC amplification, PIK3CA , and TP53 mutations, and extrinsic factors, metabolic stresses imposed by the microenvironment, such as hypoxia, oxidative stress, acidosis, contribute to different metabolic programming phenotypes in metastatic breast cancer
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