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Taurine (Tau) is abundant in macrophages and is mainly acquired through uptake, and its function is more closely related to antioxidation and the maintenance of organelle homeostasis
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Of note, GLS1 inhibition causes an elevation of the ROS level and induces GPT2 expression via ATF4, which again implies the importance of ATF4-mediated metabolic adaption during glutamine starvation
Month 3 and Beyond: This is the phase of systemic support
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