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Journal of Endocrinology and Metabolism (2013) 3
GLUT4 upregulation depends on stable NAD+ levels, further supporting the core mechanism of nicotinamide metabolism and NAD+ elevation
This is probably explained by the fact that S-adenosylmethionine (SAM), which is important for many epigenetic processes, is regenerated by methylcobalamin, whereas cyanocobalamin reduces it (as we explored above)
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