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Your doctor may recommend a GLP-1 agonist if you: Have type 2 diabetes and need better blood sugar control after meals Need to lose weight to improve your diabetes management Have cardiovascular disease or are at high risk for heart problems Have chronic kidney disease (certain GLP-1s have kidney-protective benefits) Havent reached your blood sugar targets with metformin alone Want to delay or avoid starting insulin therapy Do GLP-1 Agonists Help with Type 1 or Type 1.5 Diabetes