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Pancreatic DPP-4 As well as influencing glucose homeostasis through its more widespread systemic effects, as discussed above, there is some evidence to suggest that DPP-4 may have local actions in the endocrine pancreas
A randomized controlled trial from 2021 found that oral GSH supplementation improved insulin sensitivity in obese subjects with and without T2DM, although it didnt alter other markers of oxidative stress
Importantly, research links lower glutathione status with age-related decline and higher health risk in older adultsmaking proactive, personalized support especially valuable over time
In one study funded by Eli Lilly, people who took 4.5 mg of dulaglutide had more weight loss (about 10 lb) than those on 1.5 mg (a little less than 7 lb) after 36 weeks on the drug
