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Melatonin and sepsis Sepsis is a major cause of morbidity and mortality in newborns, born both preterm and at term, with an incidence of 110 cases per 1000 live births and a mortality rate as high as 20% observed in very preterm newborns 103
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This peripheral inflammation is a known driver of neuroinflammation, which is implicated in mood disorders, cognitive decline, and neurodegenerative diseases
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