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At the cellular level, vitamin D3 attenuated doxorubicin-induced senescence in human aortic endothelial cells by upregulating IL-10 and FOXO3a expression through the pAMPK/SIRT1/FOXO3a signaling pathway [180]
L.LalaA.TrivieriM
Aging Cell 15 , 522530 (2016)
Ask a close friend, companion, spouse, or relative to learn how to administer vitamin B12 shots, or at least hold a mirror for you while you give yourself the injection, and rub out the pain afterwards to prevent bruising and other painful side effects
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