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This "energy sink" literally starves the brain, heart, and skeletal muscles of energy, directly causing the hallmark symptom of post-exertional malaise (PEM) and the severe exercise intolerance seen in these conditions
Beyond primary mitochondrial disorders, in liver mitochondria, MT localizes to the intermembrane space and can be imported into the organelle, where its N-terminal -domain delivers zinc to the electron transport chain, inhibiting respiration in a tissue-specific and zinc-dependent manner
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But in this study, BPC 157 helped keep that damage in check by calming inflammation and reducing oxidative stress, two major culprits in tissue damage and aging
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