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Those with a family history of diabetes, elevated fasting glucose levels, or insulin resistance markers (such as elevated fasting insulin or HOMA-IR scores) may particularly benefit from preserving metformin's glucose-lowering effects while adding tirzepatide's hunger-suppressing properties
Glatiramer acetate (GA) is an exception. That is because GA (Copaxone, Teva) is classified as pregnancy category B, the safest among DMTs
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