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6 weeks of progressive ladder-climbing RT (8 climbs, progression from 50% to 100% maximal carrying load (MCL), 3 times per week) mitigates the rise in reactive oxygen species production, as represented by lipid peroxidation/malondialdehyde levels in the brain tissue of an AD rodent model (zbeyli et al., 2017)

The seven-day half-life is consistent enough across populations that it reliably supports weekly dosing for nearly everyone

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On the second day, one of these objects was replaced by a different new object, and rats were left again to explore the 2 objects