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Although research has demonstrated the therapeutic potential of Chinese medicine in treating depression, inconsistencies in experimental design, sample selection, and data analysis methods have led to significant heterogeneity in results

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Endocrinology 146, 22552264

For instance, activation of Sirt1 reduced toxin-induced neuronal death, whereas inhibition of Sirt2 ameliorated S-mediated cell death in PD models (Figure 3) ( FIGURE 3 Glial cytoplasmic inclusion of S is the pathological hallmark of multiple system atrophy