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Clinical trials have not identified increased urination as a significant adverse event requiring specific monitoring for GLP-1 receptor agonists

Cruz A, Mota P, Ramos C, Pires RF, Mendes C, Silva JP, et al
Clinical trials reveal that 4.6 times more patients achieved 15% weight loss and 6.4 times more patients achieved 20% weight loss with Wegovy than with liraglutide 3 mg at 68 weeks

The initial dose for many patients is 2.5 mg once weekly, which is often increased over time based on tolerance and treatment goals

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