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Despite these promising findings, further research is necessary to establish their long-term efficacy, optimal dosing strategies, and potential synergistic interactions of GLP-1RAs with existing pain management therapies

A study published in 2025, in which researchers interviewed 29 users of the drug, found that "participants were generally unconcerned with long-term adverse effects and instead perceived that [melanotan II] was protective against skin cancer by preventing sunburn"

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Benefits of Collagen for Skin 1