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Propensity-matching analysis using data from the SUSTAIN (subcutaneous semaglutide) and PIONEER (oral semaglutide) programs demonstrated that exposureresponse relationships for efficacy and safety were consistent between oral and subcutaneous semaglutide (Fig
2.2 Treatment and tolerance tests Male and female mice (22- to 25-week-old) were placed in clean cages and food withheld for five hours
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