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History of pancreatitis is a relative contraindication
Comorbid conditions such as type 2 diabetes, hypertension, or sleep apnea may require indefinite GLP-1 continuation for cardiovascular and metabolic protection independent of weight loss goals
DSIP-CBBBP shows a better restorative effect than DSIP on neurotransmitter imbalance and the potential to enhance sleep
Chronically elevated cortisol promotes central obesity by stimulating fat accumulation in visceral depots while causing muscle wasting in the extremities
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