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Molecules , 19(11), 1906619077
MBP: Myelin basic protein
The ultimate goal is to generate clinical evidence that leads to official changes in treatment guidelines, ensuring that injection frequency is based on patient-reported symptoms and individual clinical response, rather than solely on national blanket protocols
Perez-Leighton, Butterick-Peterson, Billington, and Kotz (2013) proposed that throughout development of obesity, there are changes in orexinergic signaling, perhaps reducing orexinergic signaling gain by changes in synaptic plasticity, which continue to change orexin system responsiveness and promote further development of obesity
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