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H., Li, A
Following chronic (6 week) feeding with an ethanol-containing liquid diet, the Gclm KO mice were unexpectedly found to be protected against steatosis despite showing increased oxidative stress (as reflected in elevated levels of CYP2E1 and protein carbonyls)
These include activation of TLR signaling pathways, responses to oxidative and heat stress, execution of phagocytic functions, participation in immune adhesion, and evasion of immune surveillance via apoptosis
Physiol.-Lung Cell
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