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In short: B12 shots are used because they deliver vitamin B12 faster, more reliably, and more efficiently than oral supplements, especially if you have an absorption issue
The substrate-binding site recognizes the consensus sequence LXGGX (the amino acid residues of the substrate are numbered P4P3P2P1P1P2 around the cleavage site, denoted by the downwards arrow)

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however, the results are clear and show that gene polymorphisms encoding GSTs are associated with the development of type 1 DM and disease-related risk factors [31]
