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Oxidative stress gene expression, DNA methylation, and gut microbiota interaction trigger Crohns disease: a multi-omics Mendelian randomization study

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Gene expression profiling revealed distinct apoptotic pathways: low-dose exposure triggers apoptosis through cellular stress responses, while high-dose exposure primarily activates it via direct DNA damage (160)

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MK-677 doesnt affect those hormones but does impair insulin sensitivity

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J Clin Med (2021) 10:5677

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