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Chronic glucagon-like peptide-1 infusion sustains left ventricular systolic function and prolongs survival in the spontaneously hypertensive, heart failure-prone rat
Senior Biological Defense Coverage (BDC) Modeling A systems-level map of which biological pathways decline first, and how layered interventions can support them
Although SERMs are a promising approach to treating estrogen-deficient skin wounds given that they can selectively target estrogen receptors in specific tissues, this also means that their effects may be limited to specific cell types or tissues
Particularly, liraglutide attenuates pre-established atherosclerosis throughout the aorta and aortic root in ApoE -/- mice via increasing macrophage polarization into anti-inflammatory macrophages and by reducing the number of pro-inflammatory macrophages [92]
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