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3 Results 3.1 Assessment of data quality The quality of patient sample data was assessed using pooled QC urine samples analysed before, during, and after each analytical batch to mitigate significant instrumentation or analytical errors

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It binds IGFBP-1, IGFBP-2, IGFBP-4, IGFBP-5, and IGFBP-6 with somewhat lower but still substantial affinity

In contrast, more than 50% Cu 2+ was released from ATA@Cu NPs after 30 min incubation at pH 6.0, which was further increased to more than 70% after 2 h incubation at pH 6.0