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Additionally, the cyclic trisulfide structure of LASSS, as opposed to the linear trisulfides such as GSSSG and cysteine trisulfide (Cys-SSS-Cys), could guarantee the unique reactivity of LASSS (see again Figure 1a for chemical structures)

The full UCN1/CART co-localization in the EWcp, along with their elevated levels in high alcohol preference mice implies a shared and significant role in controlling alcohol consumption and associated behaviors

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Michalec K, Mysiorek C, Kuntz M, Brzowski V, Szczepankiewicz AA, Wilczyski GM, et al