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Gastrointestinal bleeding, ulcer disease, and hemorrhagic stroke remain clinically significant risks, particularly in older adults

This can cause irregular periods, very heavy bleeding, or longer cycles

For patients without known thyroid disease , baseline thyroid function testing (TSH at minimum) can be considered before initiating Mounjaro if there are symptoms suggestive of thyroid dysfunction or risk factors such as family history, autoimmune conditions, or previous thyroid surgery

The association between obesity and altered sense of taste certainly requires further research, but might be a promising target for the modulation of food preferences and overeating