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The safety profile so far looks consistent with other approved GLP-1 drugs, with no new red flags
Some patients may find it challenging to consume adequate nutrition within restricted eating periods, potentially leading to nutrient deficiencies or excessive weight loss
LucasSOmataYHofmannJBttcherMIljazovicASarterKet al
This supports expanding its use to all overweight or obese patients with atherosclerotic cardiovascular disease, revising BMI-based prescription limits to focus on reducing cardiovascular risk, and positioning GLP-1RAs as an important part of secondary prevention for heart disease
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