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Thus, the three mechanisms of oxidative stress, inflammation, and alpha-synuclein aggregation are intimately interrelated
No high-quality clinical trials have specifically investigated microdosing as a therapeutic strategy
10.1684/epd.2021.1406 8
For quality control, we excluded participants who (1) have excess relatedness (more than 10 putative third-degree relatives), (2) have inconsistent information about sex based on genotyping and self-report, (3) have sex-chromosomes not XX or XY, (4) have poor-quality genotyping based on heterozygosity and missing rates, or (5) have withdrawn from UK Biobank
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